Alexey Vuinyukov

Moscow State University Of Fine Chemical Technology, Russian Federation

Biography:

Since 2018 I have been a researcher at the laboratory of superionics at the Institute for Problems of Chemical

Physics. From November 2012 to the present, I have been working (part-time) at the Laboratory of Organophosphorus Compounds of the Institute of Physiologically Active Compounds of the Academy of Sciences of the Russian Academy of Sciences as a researcher. At the moment, my work is devoted to the development of methods for the preparation and study of new functional materials based on low molecular weight and polymeric calixarene sulfonic acids and their salts for electrochemical devices (sensors, fuel cells, supercapacitors), as well as the search for new physiologically active substances and convenient procedures for their preparation. I am a co-author of 17 scientific publications, including 9 articles in peer-reviewed journals (Journal of General Chemistry, Phosphorus, Sulfur, Silicon and Related elements. Mendeleev Communication, Solid State Ionics, Biochemical and Biophysical Research Communications ), and 8 abstracts (plenary, invited, sectional, poster) at Russian and international conferences.

From 2014 to 2017 he was a co-executor of the RFBR President's grant No. 15-03-06062 "Creation of a general methodology for the synthesis of cyclic phosphoisosteres of amino acids and peptides" under the leadership of V.V. Ragulin. Since the beginning of 2018, he was the head of the RFBR grant No. 18-03-01123 "Phosphine modification of PGP and GPE tripeptides and the study of their neuroprotective properties" and No. 18-33-00643

"Development of a one-pot procedure for obtaining phosphinic acids, analogs of the HIV-1 protease inhibitor (Completed successfully). From 2018 to 2020, he was a co-executor of the Russian Science Foundation grant No.

Research Interest(s):
Calixarenes, polymerization of calixarenes, obtaining new polymeric materialsbased on 25,26,27,28-tetrahexyloxy-5,11,17,23-tetrasulfocalix [4] arene, amidoalkylation of

hydrophosphoryl compounds, Kabachnik-Fields reaction and its amide variant (Oleksizhin reaction), carbamate variant of amidoalkylation of hydrophosphoryl compounds, single amidoalkylation of phosphorous acid, double amidoalkylation of hydrophosphoryl compounds and preparation of α-aminophosphinic acids of symmetric and asymmetric structure, preparation of a number of cyclic phosphine-containing non-peptide analogs of HIV-1 inhibitor and study analogs of natural amino acids, obtaining phosphinic acid dipeptides, studying physiological activity and searching for practical application of aminophosphoryl compounds of various structures.